Do you have a deep feeling that after a certain age, you will suddenly realize that you are "old very quickly"? Huang Hui, a specialist in thoracic and critical care, said that aging is an inevitable natural phenomenon, but as long as you exceed a point, your brain will be as anxious as if you fall off a cliff and "collapse degeneration", which may even affect your life. In this regard, Huang Hui teaches you six ways to delay aging, so that you can stay healthy and energetic and not aging quickly.

The border point of brain aging

The border point of brain aging refers to the age point where brain function will experience an acute decline in life. Huang pointed out that different studies may have different definitions and measurement methods, but generally there are several boundaries:

. The 70-year-old

The 2022 British Theatre Bridge University Research Team published a study on Clonal dynamics of haematopoiesis across the human lifespan in Nature, exploring why humans will age cliff-like at the age of 70. The relationship between cliff-like aging and hydratin protein can be traced back to hematopoietic tumour cells.

The accumulation of molecular injury is progressive and enduring throughout the life cycle, including "telomerular grinding", "body cell skew", "external transmission changes" and "oxidative reaction" intensification. After the gradual accumulation of this molecular injury reached the age of 70, a large amount of toxin waste increased to the valve link, but it was still not solved, resulting in a large number of physical cells dying!

. A study published in the sub-blog of Nature, 54 years old and 72 years old, points out that the brain will have two aging transformation points in middle age and old age, namely 54 years old and 72 years old. The study found that under the excessive expression of a certain gene (Vimar/RAP1GDS1), the brain produces a "SASP protein quality" and is about 54 years old. It begins with the fragmentation of the particle, the calcinia in the cells, and the decrease in energy transfer. These conditions remain accumulated to about 72 years, resulting in accelerated brain aging, reduced recognition function and shortened life.

. 34, 60, 78,

This is a study published in the 2019 magazine "Natural Medicine" Undulating changes in human plasma protein profiles across the lifespan. It analyzed 2,925 blood proteins in 4,263 subjects aged 18-95, and found that they showed nonlinear changes in their age growth. :(a) The sudden aging at the age of 34 is most obvious in the "value": scientific research believes that this is because proteins involved in structural pathways are greatly adjusted, such as proteins related to extracellular matrix are greatly reduced. This means the loss of gelatin, and your face muscles begin to collapse, your skin begins to relax, losing the fullness, flexibility and lust of your youth.

(b) The collapsed aging of 60 and 78 years of age, which is 60 and 78 years of age, is not only on the surface of the skin, but is most obvious in "healthy" aging:. At the age of 60, hormone activity, binding function and blood pathway-related proteins changed a large amount of flow first, the most intense. ． At the age of 78, blood pathways and bone form protein signals transmitted a large number of obstacle changes, the most intense.

Researchers found that the protein peaks at the age of 60 and 78 are mainly protein fluctuations related to diseases. The junk protein related to aging diseases such as Alzheimer's disease (AD), cardiovascular disease (CVD) has obviously increased too much, preventing neuronal conduction materials and leading to severe rapid aging of internal organs. These protein peaks are related to the occurrence of diseases and the expression of aging genes, and ultimately lead to three waves of cliff-like aging in the human body.

{twenty three} {twenty four}

6 Methods: Delay aging

How to delay aging? Huang shares 6 methods to keep you healthy and energetic and not aging quickly.

1. Control blood sugar, blood lipids, blood pressure, and avoid smoke. Most fatal diseases are related to blood vessels, such as coronary heart disease, myocardial infarction, spinal sclerosis, brain wind, etc. Blood vessels are the delivery system of the human body, which delivers nutrients and oxygen to the organs and discharges the graft waste at the same time. It is important to protect blood vessels from aging, control blood sugar, blood lipids, and blood pressure, avoid smoke, and reduce the infiltration of harmful substances.

. Control blood sugar: "Hyperglycemia" is one of the important risk factors that cause brain aging. It can damage neurons and blood vessels, leading to decreased cognitive function and dementia. To control blood sugar, it is recommended that you check your blood sugar regularly, especially if you have diabetes or pre-diabetic risks. You should also pay attention to your diet, eat less high-sugar, high-oil and high-salt foods, and eat more foods rich in fiber and antioxidants, such as whole grains, beans, vegetables and fruits.

. Control of blood lipids: "Hyperlipids" are one of the important risk factors that cause atherosclerosis and cardiovascular and brain diseases, which can increase the risk of brain hypoxia and bleeding. In order to control blood lipids, it is recommended that you measure fasting blood lipids at least once a year and evaluate the risks of cardiovascular disease. You should also reduce the intake of fatty acids and trans fatty acids, and eat more foods rich in fatty acids and Omega-3 fatty acids, such as fruit, olive oil, fish, etc.

. Control blood pressure: "Hypertension" is one of the most important risk factors that cause brain aging. It can damage the microcirculation and neuronal functions of the brain, resulting in decreased cognitive function and middle age.. To control blood pressure, it is recommended that you measure blood pressure at least once a year and evaluate the risk of cardiovascular disease. You should also reduce the intake of salt and eat more foods rich in trace elements such as pita, calcium, and tart, such as mushrooms, seaweed, celery, bananas, etc.

. Avoid smoking: Smoking is one of the important risk factors that cause brain aging. It can increase oxidative response, damage the endothelium of the blood vessels, promote thrombosis, and increase the risk of brain ischemia and bleeding. Avoiding smoking can reduce the risk of cardiovascular disease, improve blood supply to the brain, and improve cognitive function.

2. Persisting in sports is not only about exercising the body, but also about exercising the brain. Exercise can promote blood circulation, allowing more oxygen and blood to be delivered to the brain, providing a nourishing environment for brain cells. Exercise can also stimulate the brain to secrete some beneficial chemical substances such as endorphins, serotonin and dopamine, which can improve our mood, concentration and memory. Therefore, if you perform moderate aerobic exercise for more than 30 minutes every Friday to seven days a week, daily activities cannot replace the effects of exercise. Exercise can improve organ function, reduce cardiovascular risks, and improve memory.

3. Endless learning is the best way to keep your brain alive and flexible. Any new learning activity will form new neural connections in the brain, which may help us avoid brain damage related to dementia. It is recommended to learn a little new thing every day, whether it is a new language, a new musical instrument, a new chess game, a new book, or a new dance, it is conducive to improving brain function and stimulating the formation of new neural elements. Therefore, continuous learning activities help maintain mental activity and reduce intellectual degeneration. And it is a good way to train memory, attention and decision-making skills often in mail, reading papers, digital games, etc.

4. Participation in social interaction is very important for adults. Don’t isolate yourself after middle age. Establishing social and emotional connections with others can reduce the risk of disease caused by aging. People with larger social networks have better connections in their brains. Knowing new friends can make your head clear, change your way of thinking, and gain new feelings and ideas. These are all brain-slip sliders. Therefore, it is necessary to maintain good interactions with colleagues, family members and friends.

5. Diet health researchers have found that limiting the intake of heat can prolong life. People who often consume high heat have a 2-fold increase in death risk and 4-fold increase in cancer risk than those who consume less heat. If you are based on plant-based foods, eat more fruits and beans, and ingesting a small amount of fish is beneficial to your health.

6. Regular physical examinations are necessary for middle-aged and elderly people. Physical examination can detect potential diseases and understand the extent to which the disease damages the organs. For people with basic diseases, physical examinations should be positive. For example, patients with hypertension need to undergo cardiac imaging, cardiac ultrasound, kidney and vascular ultrasound, biochemical blood tests and brain MRI/CT to detect the impact of cliff-type aging on the organs in advance.

The above methods can help us extend the aging process and maintain health and vitality.